Background: Burns most often occur at home and found that second degree burns is the highest
prevalence The process of wound healing can be accelerated by using traditional medicines, one of
them is a plant called Binahong (Anredera cordifolia (Ten.) Steenis)
The objective: The aim of this research were to study the effectivity of binahong (Anredera Cordifolia
(Ten) Steenis) leaf extract ointment on burn wound and to study the differences activity to binahong
leaf extract ointment (Anredera cordifolia (Ten) Steenis) with concentration 10%, 20 % dan 40%.
The method: The Randomize Control Triall is applied. the subject in this research were 40 wistar
rats chosen by random method, devided into five groups, namely negative control, positive control
and tretment group with concentration 10%, 20 % dan 40% of binahong leaf extract ointment. Burn
induced in this research is scalds, 2x2 cm size. All samples were induced with second degree burn for
21 days. The healing was assessed with macroscopic (Sussman Wound Healing Tool ) and
microscopic (degree of collagen formation, degree of new epitelization and number of
neovascularization)
The analysis: One Way ANOVA analysis showed no significant difference in wound healing
macroscopically with p> 0.05 were obtained the results of Mann Whitney test p = 0.037, which means
there is no difference between the control group picture of necrosis negative with the positive control
group.
The result: The results of this study did not reveal any significant differences in healing of seconddegree
thermal

burns in rats whereas the macroscopic microscopic observations were no significant
differences in angiogenesis. Based on the clinical picture SEDB 40% had clinical features healing
second-degree thermal burns better than the other group.

Keywords: Binahong (Anredera cordifolia (Ten.) Steenis), Leaf Extract Ointment Binahong (ESDB),
burns, Sussman Wound Healing Tool.

• OINTMENT LEAF EXTRACT BINAHONG ( ANREDERA CORDIFOLIA ( TEN ) STEENIS ) AGAINST THE BURN WOUND HEALING GRADE 2 THERMAL